HUBUNGAN EKSPRESI BETA CATENIN (Β-CATENIN) DENGAN DERAJAT HISTOPATOLOGI PADA KARSINOMA ENDOMETRIUM TIPE I
Abstract
Karsinoma endometrium adalah keganasan pada traktus genitalia wanita dengan trend kejadian yang meningkat. Penelitian ini bertujuan untuk mengevaluasi hubungan antara ekspresi β-catenin dengan derajat histopatologi pada Karsinoma endometrium Tipe I. Penelitian ini dilakukan pada Laboratorium Patologi Anatomi Fakultas Kedokteran Universitas Hasanuddin dengan mengambil sampel secara stratified sampling dari Januari 2017-Desember 2017. Dilakukan teknik pewarnaan imunohistokimia pada 49 sampel penelitian yang terkumpul, dilanjutkan dengan mengevaluasi skor ekspresi β-catenin yang terwarnai pada inti dan sitoplasma sel-sel tumor. Hasil uji statistik diperoleh nilai p = 0,694 (p > 0,05), bahwa tidak terdapat perbedaan yang bermakna antara skor ekspresi β-catenin dengan derajat histopatologi pada Karsinoma Endometrium Tipe I.
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