https://ak3.sarpras.unair.ac.id/assets/rekomendasi/ https://bce.unpad.ac.id/top/ https://pendfisika.ulm.ac.id/wp-content/thai/ https://sapasko.kemenpora.go.id/ https://ak3.sarpras.unair.ac.id/assets/berita/ https://lms.stmik-dci.ac.id/blog/cache/ https://elitbang.depok.go.id/user/sbo/ http://p4m.pnl.ac.id/ https://pastiberaksi.sulselprov.go.id/ https://elitbang.depok.go.id/ https://wonosari.bondowosokab.go.id/pelayanan/ slot gacor situs slot gacor pertanian.bondowosokab.go.id/ https://elitbang.depok.go.id/assets/ https://simaster.wonosobokab.go.id/obc4d/ https://cms-bpsdubm.kemenkumham.go.id/json/ https://elakip2023.slemankab.go.id/modules/obc4d/ https://kinerja.iainambon.ac.id/ https://corinnemartin.com/ https://thedevilsrejects.com/ https://www.ehazira.net/ https://henantwinespirits.com/ https://majormagnetgame.com/ https://grunkamunka.com/ https://villatente.com/ https://exper-tr.com/ https://bkd.iainambon.ac.id/assets/ https://mi.aikom.ac.id/assets/ https://www.gorevdeyukselmesinavi.com.tr/ https://bkad.bengkuluutarakab.go.id/wp-content/themes/ https://compchem.ub.ac.id/ https://pastiberaksi.sulselprov.go.id/sgacor/ https://lihtr.unair.ac.id/assets/ https://geliatairlangga.unair.ac.id/toto/ https://e-kkn.unila.ac.id/assets/ https://simlp2mv2.unm.ac.id/gacor/ https://e-kkn.unila.ac.id/gacor/ https://e-kkn.unila.ac.id/about/ https://pafirembang.com/ https://pafijaktim.org/ https://pafislawi.org/ https://pafilasem.org/ https://dinkes.bondowosokab.go.id/dinkes/x777/ https://guvenlunapark.com/ https://pafikediri.com/
The Effectiveness of Turmeric (Curcuma domestica) in Decreasing The Risk of Atherosclerosis | Ar rahmah | Preventif: Jurnal Kesehatan Masyarakat

The Effectiveness of Turmeric (Curcuma domestica) in Decreasing The Risk of Atherosclerosis

Arsyka Hunjri Ar rahmah

Abstract


Every year more than 36 million people die due to Non-Communicable Diseases (NCD). Globally, the number one cause of death for NCD every year is cardiovascular disease. Coronary heart disease, heart failure, hypertension and stroke are cardiovascular diseases. Atherosclerosis can be a cause of cardiovascular disease. One of the therapies that can be done to treat atherosclerosis is curcumin compound. Curcumin is an active compound in turmeric (Curcuma domestica) which functions in reducing cholesterol, antioxidant, antitoxin and anti-inflammatory. Therefore, the potential effect of curcumin can be an alternative therapy to reduce the risk of atherosclerosis. This study aims to prove the effectiveness of turmeric as an alternative therapy in reducing the risk of atherosclerosis. This type of research is a descriptive form of literature study that is made using secondary data in the form of sources obtained from library studies. The method used is collecting research results from various journals, case reports and research articles. From several studies conducted on humans, curcumin is safe to use and does not show toxic effects up to a dose of 500 mg given 2 times a day for 30 days. Curcuminoids found in turmeric have benefits as anti-inflammatory and antioxidant so that they can be used as alternative therapies for atherosclerosis.


Keywords


aterosklerosis, curcuma domestica, kurkumin, rimpang kunyit

Full Text:

PDF

References


 

1. Kemenkes RI. Situasi kesehatan jantung. Pus data dan Inf Kementeri Kesehat RI. 2014;3.

2. Shah PK, Lecis D. Inflammation in atherosclerotic cardiovascular disease. F1000Research. 2019;8:1402.

3. Butt SA, Jeppesen JL, Torp‐Pedersen C, Sam F, Gislason GH, Jacobsen S, et al. Cardiovascular Manifestations of Systemic Sclerosis: A Danish Nationwide Cohort Study. J Am Heart Assoc. 2019;8(17).

4. Förstermann U, Xia N, Li H. Roles of Vascular Oxidative Stress and Nitric Oxide in the Pathogenesis of Atherosclerosis. Circ Res. 2017;120(4):713–36.

5. Mohammad Alkhalil. Mechanistic Insights to Target Atherosclerosis Residual Risk. Curr Probl Cardiol. 2019;

6. Herrington W, Lacey B, Sherliker P, Armitage J, Lewington S. Epidemiology of Atherosclerosis and the Potential to Reduce the Global Burden of Atherothrombotic Disease. Circ Res. 2016;118(4):535–47.

7. Lintong PM. Perkembangan Konsep Patogenesis Aterosklerosis. J Biomedik. 2009;1(1):12–22.

8. Yuan Shan C, Iskandar Y. Studi Kandungan Kimia Dan Aktivitas Farmakologi Tanaman Kunyit (Curcuma longa L.). 2018;16:547–55.

9. Perkins K, Sahy W, Beckett RD. Efficacy of Curcuma for Treatment of Osteoarthritis. Journl Evid Based Complement Altern Med. 2016;1–10.

10.Hewlings S, Kalman D. Curcumin: A Review of Its’ Effects on Human Health. Foods. 2017;6(10):92.

11.Hatamipour M, Ramezani M, Tabassi SAS, Johnston TP, Sahebkar A. Demethoxycurcumin: A naturally occurring curcumin analogue for treating non‐cancerous diseases. J Cell Physiol. 2019;234(11):19320–30.

12.Deopujari R, Dixit A. The Study Of Age Related Changes In Coronary Arteries And Its Relevance To The Atherosclerosis. J Anat Soc India. 2010;59(2):192–6.

13.Spence JD, Pilote L. Importance of sex and gender in atherosclerosis and cardiovascular disease. Atherosclerosis [Internet]. 2015;241(1):208–10. Available from: http://dx.doi.org/10.1016/j.atherosclerosis.2015.04.806

14.Aziz M. Pathogenesis of Atherosclerosis A Review. iMedPub J. 2016;2(3):1–6.

15.Stancel N, Chen CC, Ke LY, Chu CS, Lu J, Sawamura T, et al. Interplay between CRP, Atherogenic LDL, And LOX-1 and its potential role in the pathogenesis of atherosclerosis. Clin Chem. 2016;62(2):320–7.

16.Mutiah R. Evidence Based Kurkumin Dari Tanaman Kunyit (Curcuma Longa) SEBAGAI TERAPI KANKER. 1992;1(1):28–41.

17.Dosoky NS, Setzer WN. Chemical Composition and Biological Activities of Essential Oils of Curcuma Species. Nutrients. 2018;10(1):10–7.

18.Shimizu K, Funamoto M, Sunagawa Y, Shimizu S, Katanasaka Y, Miyazaki Y, et al.Anti-inflammatory Action of Curcumin and Its Use in the Treatment of Lifestyle-related Diseases. Cardiovasc Pharmacother. 2019;14(2):117–22.

19.Vaughn AR, Branum A, Sivamani RK. Effects of Turmeric ( Curcuma longa ) on Skin Health : A Systematic Review of the Clinical Evidence. Phyther Res. 2016;30(8):1243–64.

20.Griffiths K, Aggarwal B, Singh R, Buttar H, Wilson D, De Meester F. Food Antioxidants and Their Anti-Inflammatory Properties: A Potential Role in Cardiovascular Diseases and Cancer Prevention. Diseases. 2016;4(4):28.

21.Hartati, Rusny, Mashuri Masri. Pengaruh Pemberian Bubuk Kunyit (Curcuma domestica) Terhadap Pertumbuhan Mencit (Mus musculus L. ) ICR Dari Hasil Perkawinan Outbreading 1. Pros Semin Nasionar Mikrobiol Kesehat dan Lingkung. 2015;126–31.

22.Fahryl N, Carolia N. Kunyit ( Curcuma domestica Val ) sebagai Terapi Artritis Gout Turmeric ( Curcuma domestica Val . ) as Therapy of Gout Arthritis. Majority. 2019;8(1):251–5.

23.Soleimani V. Turmeric ( Curcuma longa ) and its major constituent ( curcumin ) as nontoxic and safe substances : Review. 2018;(September 2017):1–11.


 

 

 


Refbacks

  • There are currently no refbacks.


Copyright (c) 2019 Preventif: Jurnal Kesehatan Masyarakat

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Creative Commons License
Preventif: Jurnal Kesehatan Masyarakat by FKM UNTAD is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Based on a work at http://jurnal.untad.ac.id/jurnal/index.php/Preventif.

 

Preventif : Jurnal Kesehatan Masyarakat Indexed By :

 

 


 

 StatCounter - Free Web Tracker and Counter


View My Stats